Darmiyan
Early detection & monitoring of
Alzheimer’s disease
through BrainSeeTM
The Virtual Microscope
A Nobel Laureate approved technology
Darmiyan is developing a commercial diagnostic software platform for the early detection, monitoring and stratification of Alzheimer’s disease (AD) and other neurodegenerative disorders through an innovative magnetic resonance (MR) image analysis technology. Based on over 40 years of cutting-edge brain research, our technology can precisely quantify and detect changes in brain tissue at the cellular level in every voxel (3D pixel) of a brain MRI scan.
Product
Our novel solution, BrainSeeTM, is a Software as a Service (SaaS) platform. Doctors provide standard clinical brain MRI scans (T1, T2 FLAIR, and DWI/DTI), and BrainSee analyzes the scans in a few hours and provides detailed brain maps with exact quantification of neurodegeneration in each voxel, as well as a summary score that reflects the person’s brain health and the likelihood of future cognitive decline.
Why use BrainSee instead of PET or CSF biomarkers?
Unlike MRI machines, PET (positron emission tomography) scanners are not widely available around the world. Performing an amyloid PET scan requires injection of a very expensive radioactive tracer and involves X-Ray radiation similar to a CT (computed tomography) scan. Moreover, amyloid-beta protein is a non-specific biomarker and not very accurate in determining the prognosis of MCI. CSF (cerebrospinal fluid) sampling requires lumbar puncture, an invasive and very inconvenient procedure. Unlike PET or CSF, Darmiyan’s BrainSee solution is non-invasive, convenient, accurate, affordable, globally available, and scalable.
| Non-invasive | Convenient | Accurate | Affordable | Globally Available | Scalable | |
|---|---|---|---|---|---|---|
| Darmiyan | 😃 | 😃 | 😃 | 😃 | 😃 | 😃 |
| Amyloid PET & CSF | 😒 | 😢 | 🤨 | 😒 | 🙁 | 🤨 |
See blind testing validation results in our white paper here
Learn more about the technology here
Or watch the video below
Podcast: Riches and Niches of Cognitive Health
Team
Padideh Kamali-Zare, PhD
Chief Executive Officer
& Founder
Pavan Krishnamurthy, PhD
Head of Operations
Kaveh Vejdani, MD
Chief Medical & Technology Officer
& Co-founder
Elham Khosravi, PhD
Head of Analytics and Innovation
Thomas Liebmann, PhD
Chief Scientific Officer
& Co-founder
Hesaam Esfandyarpour, PhD
Chairman of the Board
Meet the whole team!
News and Milestones
Selected news highlights
- Dec 9-10, 2019: Presented in Innovation in Longevity Summit, Washington, DC
- Dec 4-7, 2019: Presented in CTAD 2019, San Diego, CA
- Oct 2019: US patent allowed and will publish soon
- Oct 2019: Blind testing validation results published in white paper
- Sep 2019: Released BrainSee v1.0
- Mar 2019: Won CABHI 2019 innovation award
- Nov 2018: Presented at TEDMED Hive, Palm Springs, CA
- July 2017: Started Y-Combinator program
- May 2017: Won Amgen-QB3 (MBC Biolabs) Golden Ticket award